Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit.
Who is likely to be deficient?
Vinpocetine is not an essential nutrient, so no deficiencies are possible.
How much is usually taken?
Research has typically used 30 to 60 mg per day of vinpocetine. Taking vinpocetine with
food appears to dramatically improve its absorption. 1
Are there any side effects or interactions?
Studies on vinpocetine report no serious side effects with amounts up to 60 mg per day.
2 Vinpocetine has blood-thinning effects, 3 which suggests that people
with bleeding disorders or who are taking anticoagulant or other blood-thinning medications
should consult a doctor before taking vinpocetine. However, one study found no such
interaction between vinpocetine and the anticoagulant drug warfarin. 4
Are there any drug
interactions?
Certain medicines may interact with vinpocetine. Refer to drug interactions for a list of those medicines.
References (To view, roll mouse over the "References" heading; to hide, click on the heading)
1. Lohmann A, Dingler E, Sommer W, et al. Bioavailability of vinpocetine
and interference of the time of application with food intake. Arzneimittelforschung
1992;42:914–7.
2. Hindmarch I, Fuchs HH, Erzigkeit H. Efficacy and tolerance of
vinpocetine in ambulant patients suffering from mild to moderate organic psychosyndromes.
Int Clin Psychopharmacol 1991;6:31–43.
3. Osawa M, Maruyama S. Effects of TCV-3B (vinpocetine) on blood
viscosity in ischemic cerebrovascular diseases. Ther Hung 1985;33:7–12.
4. Hitzenberger G, Sommer W, Grandt R. Influence of vinpocetine on
warfarin-induced inhibition of coagulation. Int J Clin Pharmacol Ther Toxicol
1990;28:323–8.
The information presented in Healthnotes is for informational purposes
only. It is based on scientific studies (human, animal, or in vitro), clinical
experience, or traditional usage as cited in each article. The results reported may not
necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over the counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires September 2008.
